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Welcome to Notes by Acaster Lloyd, a newsletter where you'll find our take on key research topics
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Are we blinded by standardisation?
by Arya Pimprikar and Andrew Lloyd Health state utilities are important in determining the cost-effectiveness of new treatments. We...
Aug 143 min read


How a poor evidence base can distort decision-making in cancer
New cancer treatments are typically expensive, prompting committees worldwide to evaluate their value carefully. Approval is often based...
Jul 282 min read


Three things you should know about qualitative research to support NICE submissions
Submissions to the National Institute for Health and Care Excellence (NICE) increasingly incorporate qualitative research to help...
May 212 min read


Bolt-ons and blind spots: what we’re missing in health metrics
Bolt-ons are additional dimensions that can be added to the EQ-5D-5L — a generic health-related quality of life (HRQoL) measure — with...
Apr 153 min read


Has NICE made an error in their most recent HTA Methods guidance? And is there a simple fix?
A change in the methods recommended by the National Institute for Health & Care Excellence (NICE) in 2022 seems to have introduced an...
Mar 182 min read


How item response theory can help you take patient insights even further
For many, item response theory (IRT) is a tool for selecting items for a new patient-reported outcome (PRO) or producing a short-form PRO...
Feb 183 min read
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